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Family with sequence similarity 3 member C2, pseudogene (FAM3C2P)

Target
FAM3C2P
Molecular classification
Other (Pseudogene)
01

Overview

FAM3C2P is a pseudogene belonging to the "family with sequence similarity 3" group, specifically designated as member C2[1]. As a pseudogene, it results from the duplication or mutation-inactivation of a parent coding gene and is thought to have lost the ability to produce a functional protein. Pseudogenes, including FAM3C2P, often retain high DNA sequence similarity to their functional counterparts but typically lack protein-coding capability due to frameshifts, truncations, or mutations[1][3][4]. However, some pseudogenes can acquire regulatory functions, particularly at the RNA level, by producing noncoding transcripts that may modulate parental gene expression. Pseudogenes can act as molecular sponges for microRNAs targeted to their parental genes or may generate regulatory long noncoding RNAs, but such mechanisms have been described only for a limited number of well-characterized pseudogenes—not specifically for FAM3C2P[2][3][5].

Other names
FAM3C2P
02

Mechanism of action

None known

03

Biological functions

Can act as a source or decoy for noncoding RNAs, especially by serving as a competing endogenous RNA (ceRNA) and influencing gene regulation through interactions with microRNAs.Possible regulation of parent gene expression via miRNA decoy activity, antisense transcripts, or production of regulatory long noncoding RNAs (lncRNAs)
04

Disease associations

Other (Indirect roles possible as with other pseudogenes, affecting parent genes involved in cancer, but no direct evidence for FAM3C2P specifically)

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