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Family with sequence similarity 66 member A (FAM66A)
- Target
- FAM66A
- Molecular classification
- Long non-coding RNA (lncRNA), Other
01
Overview
Family with sequence similarity 66 member A (FAM66A), also known as FAM86B2-DT, is a long non-coding RNA (lncRNA) implicated in cancer biology, particularly in the regulation of tumor metastasis in lung adenocarcinoma and the prognosis of small cell lung cancer[1]. It may participate in cell signaling pathways, notably interacting with vitamin D receptor signaling, and is under investigation for its potential role as a diagnostic or prognostic biomarker in various cancers. FAM66A is not a receptor, enzyme, or conventional druggable therapeutic target, but rather is studied for its regulatory and biomarker roles in disease[1].
- Other names
- FAM66AFAM86B2-DT
02
Biological functions
Regulation of gene expressionPotential involvement in metastasis of cancer cellsInteraction with pathways such as the vitamin D receptor signaling pathway
03
Disease associations
Cancer (with specific associations in lung adenocarcinoma, small cell lung cancer, and ovarian carcinosarcoma)
04
Biomarkers
Potential biomarker for tumor metastasis in lung adenocarcinoma[1]Potential prognostic marker in small cell lung cancer[1]
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