Target intelligence / Profile preview

Family with sequence similarity 71, member A pseudogene (ENSG00000261178)

Target
ENSG00000261178
Molecular classification
Other, pseudogene
01

Overview

Family with sequence similarity 71, member A pseudogene (ENSG00000261178), is categorized as a pseudogene—a region of DNA homologous to the FAM71A gene but does not encode a functional protein[3]. While traditionally considered "junk DNA," recent research suggests that pseudogenes can sometimes be transcribed into noncoding RNAs with possible regulatory roles, such as acting as microRNA decoys or occasionally generating small interfering RNAs that can modulate gene expression, particularly in the context of cancer[1][4]. However, this regulatory activity is not universal, and most pseudogenes, including ENSG00000261178, are not considered conventional druggable targets. Their clinical and pharmacological significance remains limited relative to protein-coding genes.

Other names
FAM71A pseudogeneFAM71A-ps
02

Biological functions

Regulatory RNA activity (possible: may produce noncoding RNAs that affect gene regulation, such as acting as microRNA decoys or generating siRNAs in some contexts)Other (may have subtle, noncoding roles, but not classical signaling or enzymatic activity)
03

Disease associations

Other (some pseudogenes have been implicated in disease progression, notably cancer, by acting as microRNA decoys and potentially regulating oncogenes and tumor suppressors; however, specific disease association for this pseudogene is not documented)

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