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Target intelligence / Profile preview
Family with sequence similarity 74 member A3 (FAM74A3)
- Target
- FAM74A3
- Molecular classification
- Other (gene/protein of unknown molecular family; not classified as receptor, kinase, channel, enzyme, transporter, or transcription factor)
01
Overview
Family with sequence similarity 74 member A3 (FAM74A3) is a poorly characterized gene encoding a putative protein of 159 amino acids. It has possible roles in cellular processes such as adhesion, migration, and proliferation. Mutations in FAM74A3 have been associated with increased risk of several cancers (including breast, ovarian, lung, and prostate cancer), intellectual disability, and autism spectrum disorder. There is currently no experimental evidence that FAM74A3 functions as a receptor, enzyme, or other canonical drug target, nor are there known interacting drugs or mechanisms of action. Its molecular family remains unclear, and it is not widely used as a biomarker or therapeutic target in clinical settings.
- Other names
- FAM74A3OTTHUMG00000067149
02
Biological functions
Cell adhesionCell migrationCell proliferation
03
Disease associations
Cancer (breast, ovarian, lung, prostate)Intellectual disabilityAutism spectrum disorderOther cancers
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