Family with sequence similarity 90 member A26 (FAM90A26)

Family with sequence similarity 90 member A26 (FAM90A26) is annotated as a **protein-coding gene** but is primarily regarded as a **pseudogene**, meaning it is a DNA sequence similar to known genes but generally considered non-functional as a protein due to disabling mutations or genomic context[1][5]. Limited experimental evidence supports that FAM90A26 encodes a functional protein in humans[1][5][7]. Gene ontology links suggest nucleic acid binding potential, but there is no clear demonstration of physiologic or pathologic function[1]. Its classification as a pseudogene suggests it may play a *regulatory RNA role*—some pseudogenes modulate gene expression via non-coding RNA transcripts, microRNA decoy activity, or antisense regulation, especially in cancer biology, but FAM90A26-specific evidence is lacking[2][6]. It is not recognized as a canonical therapeutic target (e.g., receptor, enzyme, transporter) and has no known drug interactions, disease biomarker relationship, or established molecular mechanism[1][5][6]. FAM90A26’s gene is part of a primate-specific gene family arising from duplication events, and it has a paralog called FAM90A23[1][3]. **Summary**: FAM90A26 is a non-canonical, pseudogene-class gene potentially involved in RNA regulation, but there is *no established evidence of protein-coding function, disease relevance, or therapeutic targeting*—therefore it is not a current drug target and is likely listed due to nomenclatural or annotation artifacts[1][5][2][6].

Other names

Protein FAM90A26FAM90A26FAM90A26Pfamily with sequence similarity 90, member A26, pseudogeneputative protein FAM90A26