Farnesyl diphosphate synthase pseudogene 4 (FDPSP4)

Farnesyl diphosphate synthase pseudogene 4 (FDPSP4) is a human pseudogene related to the functional *farnesyl diphosphate synthase* (FDPS), an enzyme involved in isoprenoid biosynthesis, but FDPSP4 itself does not encode a functional protein product and is categorized as a pseudogene[1]. Pseudogenes such as FDPSP4 are generally nonfunctional remnants of ancestral genes and do not serve as therapeutic targets[1]. **Additional context explaining rationale:** - **Is_target:** Pseudogenes by definition do not encode active proteins and are not considered functional therapeutic targets such as receptors, enzymes, or transporters[1]. The function and druggability described for farnesyl diphosphate synthase (FDPS) do not apply to the pseudogene FDPSP4. - **Is_incorrect:** The request is for a drug discovery target, but FDPSP4 is not itself a target. Confusion may arise due to the close naming with the functional enzyme (FDPS), which *is* a well-studied therapeutic target, notably for drugs affecting bone resorption and cancer via the mevalonate pathway[3][4]. However, FDPSP4 is a pseudogene without therapeutic or biological function[1].

Other names

CHR39BFDPSL4FPSL4cholesterol-repressible protein 39Bfarnesyl diphosphate synthase-like 4farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase) pseudogene