Target intelligence / Profile preview

FAS-associated factor 1

Molecular classification: Ubiquitin-like protein, Ubiquitin-associated protein, Scaffold protein

Overview

FAS-associated factor 1 (FAF1) is a protein that regulates apoptosis, protein degradation, and immune responses. It interacts with the FAS receptor to enhance apoptosis and also participates in ubiquitin-mediated protein degradation. It has been implicated in tumorigenesis and Joubert Syndrome.

Biological functions

Apoptosis regulationProtein degradationUbiquitinationImmune response modulationERAD

Disease associations

CancerJoubert Syndrome

Safety considerations

TumorigenesisContext-dependent pro- or anti-apoptotic role

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