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Target intelligence / Profile preview
Fascin actin-bundling protein 1 pseudogene 1 (FSCN1P1)
- Target
- FSCN1P1
- Molecular classification
- Pseudogene, Non-coding RNA gene
01
Overview
Fascin actin-bundling protein 1 pseudogene 1 (FSCN1P1) is a non-protein-coding pseudogene located in the human genome. Although unable to produce a functional fascin protein, some research suggests stage-specific upregulation of FSCN1P1 in certain cancers, with possible involvement in cellular reprogramming and differentiation within cancer gene regulatory networks. Like other pseudogenes, it may exert an indirect regulatory function—such as acting as a competing endogenous RNA or influencing post-transcriptional regulation—but is not itself a protein or classic therapeutic target.
- Other names
- HGNC:49669NCBI Gene:145989Ensembl:ENSG00000261559
02
Mechanism of action
Not applicable; not a druggable target by classical mechanisms since it is non-coding
03
Biological functions
Possible regulatory function in gene expression or cellular differentiation as shown for some cancer-associated pseudogenes, but does not itself produce proteinIndirect role in cellular reprogramming and oncogenic processes as observed in specific cancers like stage II oesophageal carcinoma
04
Disease associations
Regulation of cellular differentiation and possibly oncogenesis (not as a direct functional protein, but via effects on gene regulatory networks in cancer, e.g., oesophageal carcinoma)
05
Biomarkers
FSCN1P1 was reported as upregulated in stage II oesophageal carcinoma and included in the combinatorial expression landscape of pseudogenes serving as potential biomarkers for oncogenesis and poor prognosis
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