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Target intelligence / Profile preview
Fast Skeletal Muscle Troponin Complex (fsTroponin Complex)
- Target
- fsTroponin Complex
- Molecular classification
- Protein complex
01
Overview
The fast skeletal muscle troponin complex is a heterotrimeric protein complex essential for the regulation of contraction in fast-twitch (Type II) skeletal muscle fibers. It is composed of three subunits: troponin C (TnC), troponin I (TnI), and troponin T (TnT). Each subunit has a specific role in the calcium-dependent regulation of actomyosin ATPase activity, which underlies muscle contraction.
- Other names
- Troponin Complex (fast skeletal)Troponin (fast skeletal)fsTroponin
02
Mechanism of action
Calcium sensitization of the troponin complex
03
Biological functions
Calcium-dependent regulation of muscle contractionRegulation of actomyosin ATPase activity
04
Disease associations
Neuromuscular disorders
05
Interacting drugs
CK-2017357
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