Fatty Acid Transporter (FAT)

Fatty acid transporters are a family of membrane-associated proteins that mediate the uptake of long-chain fatty acids into cells. These transporters play a critical role in cellular energy metabolism, lipid homeostasis, and signaling pathways. Major types include CD36, FATPs (SLC27 family), Plasma Membrane Fatty Acid-Binding Protein (FABPpm), and G Protein–Coupled Receptors such as FFAR1 and FFAR4. They are implicated in various metabolic diseases and are considered therapeutic targets.

Other names

LCFA transporterCD36FATPFABPpmFFAR1FFAR4SLC27 family

Facilitates the movement of long-chain fatty acids across cell membranes, enhancing uptake and regulating intracellular fatty acid concentrations.