Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Fel d 1 protein (Fel d 1)
- Target
- Fel d 1
- Molecular classification
- Secretoglobin, Glycoprotein, Allergen
01
Overview
Fel d 1 is the primary allergen produced by domestic cats, responsible for the majority of allergic reactions in humans exposed to cats. It is a secretoglobin protein complex, encoded by two genes, and is found predominantly in cat saliva, sebaceous glands, skin, and other anatomical areas. While its precise physiological function remains unclear, it is hypothesized to bind lipids or steroids and acts as an immune modulator. It activates TLR4/MD2 and TLR2 signaling pathways, contributing to allergic inflammation.
- Other names
- Felis domesticus allergen 1Cat allergen 1Cat major allergen
02
Biological functions
Lipid binding (potential)Steroid binding (potential)Semiochemical carrier (potential)Immune modulationTLR4/MD2 activationTLR2 activation
03
Disease associations
AllergyAsthmaAllergic rhinitis
04
Safety considerations
Induction of allergic reactionsExacerbation of asthma
05
Biomarkers
IgE reactivity to Fel d 1Fel d 1 levels in environment
Beyond the preview
Go deeper on Fel d 1 protein (Fel d 1).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Fel d 1 protein (Fel d 1).