FERM domain containing 8 pseudogene 1 (FRMD8P1)

FERM domain containing 8 pseudogene 1 (FRMD8P1) is a predicted human pseudogene with sequence similarity to protein-coding FERM domain containing 8 (FRMD8). Pseudogenes like FRMD8P1 typically do not produce a functional protein, although they may occasionally have regulatory effects at the transcript level. FRMD8P1 is predicted to be involved in negative regulation of canonical Wnt signaling and localizes to the cytoskeleton and plasma membrane[3]. However, there is no experimental evidence supporting any protein function or disease association for FRMD8P1, and it is not considered a therapeutic target. FRMD8P1 is often confused with its protein-coding paralog FRMD8, which is involved in tumor necrosis factor (TNF) signaling and Wnt pathway modulation[2][6], but only FRMD8 (not FRMD8P1) has established biological and disease relevance. Pseudogenes like FRMD8P1 are primarily important for genomic research or potential gene regulation studies, not direct therapeutic targeting. Summary: FRMD8P1 is a human pseudogene related to the FERM domain-containing protein family, predicted by sequence similarity to have limited regulatory functions, but not experimentally validated or clinically targeted[3].

Other names

Putative FERM domain-containing protein FRMD8P1FRMD8P1FKSG43FERM domain-containing 8 pseudogene 1FERM domain-containing protein 8 pseudogene

None; not a drug target