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Ferric ion (Fe3+)
- Target
- Fe3+
- Molecular classification
- Inorganic Ion, Cofactor, Metabolite
01
Overview
Ferric ion (Fe3+) is a monoatomic trication of iron that plays essential roles in biological systems. It acts as a cofactor in various enzymes, is crucial for oxygen transport, DNA synthesis, and energy production. Iron deficiency involving insufficient ferric/ferrous supply is a common nutritional deficiency. Therapeutically, ferric ion is administered as intravenous iron preparations like iron-sucrose or oral agents such as ferric citrate.
- Other names
- Iron(III)Ferric cationIron(3+)Fe(III)
02
Mechanism of action
N/A
03
Biological functions
Cofactor activityOxygen transportDNA synthesisEnergy productionMetabolism
04
Disease associations
Iron deficiency anemia
05
Safety considerations
Iron overloadToxicity at high concentrationsDrug interactions (e.g., phosphate binders)
06
Interacting drugs
Iron-sucrose
1 more in the full profile.
07
Biomarkers
Ferric ion levels in bloodDietary intake (certain foods)
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