Target intelligence / Profile preview

Ferritin heavy chain 1 pseudogene 16 (FTH1P16)

Target: FTH1P16
Molecular classification: Other (processed pseudogene), Non-coding RNA (as it functions through RNA-based mechanisms[4][7])

Overview

Ferritin heavy chain 1 pseudogene 16 (FTH1P16) is a processed pseudogene related to the ferritin heavy chain 1 (FTH1) gene. Unlike the parental FTH1 gene, which encodes the heavy chain subunit of ferritin, FTH1P16 does not produce a functional ferritin protein[4][7]. Instead, it is transcriptionally active and acts primarily through non-coding RNA functions. FTH1P16 serves as a competing endogenous RNA (ceRNA), modulating the expression of FTH1 by acting as a molecular decoy for microRNAs that target FTH1. This ceRNA activity supports the regulation of iron storage protein levels and impacts cellular iron homeostasis. FTH1P16 and related pseudogenes are implicated in cancer biology, notably as tumor suppressors in prostate cancer via disruption of microRNA-mediated repression of FTH1, thus indirectly affecting iron metabolism and tumor growth[4][7]. As a pseudogene without protein-coding function, it is not considered a direct therapeutic target, and there are no known drugs interacting with FTH1P16.

Other names: Ferritin heavy polypeptide 1 pseudogene 16FTH1 pseudogene 16

Biological functions

Competing endogenous RNA (ceRNA) regulation[4][7]Regulation of iron homeostasis (via modulation of FTH1 expression, but not direct iron storage function)[4][7]Possible tumor suppressor function (by miRNA sponging in gene networks)[4][7]

Disease associations

Cancer (notably prostate cancer; implicated in tumor-suppressive regulatory networks)[4][7]Other (potentially affects cellular iron metabolism through gene regulation)[4][7]

Beyond the preview

Go deeper on Ferritin heavy chain 1 pseudogene 16 (FTH1P16).

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Drug pipeline

Explore the programs pursuing this target and their development progress.

Drug candidates
Developers
Development stage

Clinical trials

Follow the clinical studies evaluating therapies directed at this target.

Trial design
Status
Readouts

Competitive landscape

Compare approaches across drug candidates, modalities, and indications.

Programs
Modalities
Indications

Literature & evidence

Investigate the research and source evidence behind target biology and development.

Publications
Sources
Analysis

Patents

Explore patent activity around therapies and technologies addressing this target.

Patents
Assignees
Technologies

Research & analysis

Connect target biology, drug development, and emerging evidence in your research.

Biology
Development news
Analysis

Bring the full picture into focus.

See how Gosset can support your research on Ferritin heavy chain 1 pseudogene 16 (FTH1P16).

Explore the full profile