Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Ferritin heavy chain 1 pseudogene 26 (FTH1P26)
- Target
- FTH1P26
- Molecular classification
- Other, Pseudogene, Competing endogenous RNA (ceRNA)
01
Overview
Ferritin heavy chain 1 pseudogene 26 (FTH1P26) is a human pseudogene derived from the ferritin heavy chain 1 (FTH1) gene[1]. Pseudogenes of FTH1, including FTH1P26, do not encode functional protein[4][5]. Instead, they can participate in gene regulation by acting as competing endogenous RNAs (ceRNAs), sequestering microRNAs that would otherwise bind to FTH1 mRNA[4][5]. This network of FTH1 and its pseudogenes has been implicated in modulating iron homeostasis and tumor suppression, particularly in the context of prostate cancer, though the best-studied FTH1 pseudogenes for such functional roles are FTH1P11 and FTH1P16[4][5]. The specific biological or disease roles of FTH1P26 have not been individually characterized but it is assumed to be part of the broader FTH1 pseudogene family regulatory network. As a pseudogene, FTH1P26 is not a direct therapeutic target and no drugs or mechanisms of action are associated with it.
- Other names
- FTH1P26Ferritin H subunit pseudogene 26Ferritin heavy chain pseudogene 26
02
Biological functions
Regulation of parental gene expression via miRNA competitionPossible involvement in iron metabolism regulation (indirectly)Tumor suppressor activity via ceRNA network (putative, by analogy with other FTH1 pseudogenes)
03
Disease associations
Cancer (specifically, regulatory roles in prostate cancer through the ceRNA network linking FTH1 and its pseudogenes[4][5])Other (potentially broader oncological roles by regulating iron-related oxidative stress[5])
04
Biomarkers
Expression levels of FTH1 pseudogenes (as a group) may serve as biomarkers for tumor biology involving iron metabolism and ceRNA regulation[4][5], but FTH1P26 itself is not specifically named in these studies.
Beyond the preview
Go deeper on Ferritin heavy chain 1 pseudogene 26 (FTH1P26).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Ferritin heavy chain 1 pseudogene 26 (FTH1P26).