Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Ferritin heavy chain 1 pseudogene 3 (FTH1P3)
- Target
- FTH1P3
- Molecular classification
- Other (Long non-coding RNA pseudogene, lncRNA pseudogene)
01
Overview
Ferritin heavy chain 1 pseudogene 3 (FTH1P3) is an intronless pseudogene of the ferritin heavy chain 1 (FTH1) gene, located on human chromosome 2p23.3 and transcribed into a long non-coding RNA (lncRNA). The transcript contains early stop codons and does not encode a functional protein but is widely and robustly expressed in many human tissues and cell lines, much like its parental gene. FTH1P3 acts via ceRNA mechanisms by sponging microRNAs that modulate its parent FTH1 and related ferritin gene expression. Overexpression and regulatory activities of FTH1P3 have been implicated in the progression of several cancers, possibly by influencing cellular iron homeostasis, proliferation, migration, invasion, epithelial-mesenchymal transition, and drug resistance.
- Other names
- FTH1 pseudogene 3H-Ferritin pseudogene 3
02
Biological functions
Competing endogenous RNA (ceRNA) regulatory functionmiRNA "sponge" activity (modulates levels of parental FTH1 and related genes by sequestering microRNAs)Possible roles in cell differentiation and gene regulation
03
Disease associations
Cancer (reported upregulation and oncogenic roles in multiple human cancers—oral squamous cell carcinoma, uveal melanoma, glioma, breast cancer, esophageal carcinoma, cervical cancer, non-small cell lung cancer)Other (general regulatory roles in cellular differentiation and gene expression)
Beyond the preview
Go deeper on Ferritin heavy chain 1 pseudogene 3 (FTH1P3).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Ferritin heavy chain 1 pseudogene 3 (FTH1P3).