Ferritin light chain pseudogene 18 (FTLP18)

Ferritin light chain pseudogene 18 (FTLP18) is classified as a pseudogene, meaning it is a DNA sequence similar to a known functional gene (in this case, ferritin light chain) but is not believed to encode a functional protein product[1][2][4]. Pseudogenes generally do not have established biological functions, do not act as drug targets, and are not associated with disease mechanisms, known biomarkers, or therapeutic safety concerns. FTLP18 is distinguished from FTL (Ferritin light chain), which encodes the light subunit of ferritin, a functional iron-storage protein implicated in iron homeostasis and a variety of diseases[3][5]. FTLP18 is registered as an approved pseudogene locus by the HUGO Gene Nomenclature Committee[2]. No drugs or clinical biomarkers are known to interact with FTLP18, nor does it have a recognized role in human disease or biology. In summary, FTLP18 is not a therapeutic target, not a functional receptor, enzyme, transporter, or protein, and does not possess the typical data fields associated with druggable targets, biomarkers, or disease pathways. It is a noncoding pseudogene without known biological or clinical utility[2][4].

Other names

Ferritin, light polypeptide pseudogene 18FTLP18