Target intelligence / Profile preview

Fibrin Monomer

Molecular classification: Protein fragment, Coagulation factor

Overview

Fibrin monomer is a protein fragment produced during the blood coagulation process. It forms when thrombin cleaves fibrinogen, transforming it into insoluble fibrin monomers, which are essential intermediates in clot formation. Measurement of soluble fibrin monomer levels in plasma serves as an early marker for activation of coagulation and ongoing thrombosis.

Biological functions

Blood clot formationHemostasisPolymerization

Disease associations

Disseminated Intravascular Coagulation (DIC)Venous Thromboembolism (VTE)ThrombosisHypercoagulable states

Safety considerations

Elevated levels associated with increased risk of thrombosis

Biomarkers

Elevated levels in plasma indicate hypercoagulable statesEarly marker for activation of coagulation and ongoing thrombosis

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