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Target intelligence / Profile preview
Fibrous sheath CABYR-binding protein (FSCB)
- Target
- FSCB
- Molecular classification
- Other
01
Overview
Fibrous sheath CABYR-binding protein (FSCB) is a testis- and sperm-specific protein that enables calcium ion binding, is involved in negative regulation of protein sumoylation, and is believed to function in the later stages of fibrous sheath biogenesis and spermatozoa capacitation, localizing to the sperm fibrous sheath and sperm principal piece[1][2][3][4][6]. There is no established role for FSCB as a therapeutic or diagnostic target, nor are there any known interacting drugs or mechanisms of action related to pharmacology.
- Other names
- C14orf155DKFZP434F1017fibrous sheath CABYR binding proteinFSCB
02
Biological functions
Calcium ion bindingNegative regulation of protein sumoylationFibrous sheath biogenesisSpermatozoa capacitation
03
Disease associations
Other (no current strong linkage to major disease categories)
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