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Filarial worm muscle membrane

Molecular classification
Other (not a specific molecular entity)
01

Overview

"Filarial worm muscle membrane" is not the canonical name of a specific molecular target but rather refers generically to the plasma membrane surrounding the body wall muscles of filarial nematodes such as Wuchereria bancrofti and Brugia malayi. The body wall muscles are essential for motility and survival of these parasites. Research has identified specific proteins within or associated with these membranes—such as Disorganized Muscle Protein 1 (DIM-1), which is necessary for maintaining muscle integrity[6], and various ion channels and receptors involved in chemosensory signaling[4]. However, "filarial worm muscle membrane" itself does not denote a single protein, receptor, enzyme, or transporter that would be considered a standard therapeutic drug target. Instead, it describes an anatomical structure composed of multiple potential targets. Some antiparasitic agents act on components within this system by disrupting neuromuscular function or structural stability but do not interact with an entity formally named "filarial worm muscle membrane." Therefore, this term is too broad and non-specific to serve as a canonical drug discovery or pharmacological target. Summary judgment: - The entry "Filarial worm muscle membrane" is **not** considered a valid therapeutic molecular target because it lacks specificity—it refers to an anatomical feature rather than an individual molecule. - There are no common abbreviations or aliases. - It should be replaced by more precise targets such as individual ion channels/receptors/proteins found in filarial musculature if relevant for structured data extraction. - Marked **is_incorrect: true** due to lack of specificity and failure to conform with conventions for naming drug targets.

02

Biological functions

Muscle contractionMotilityStructural integrity of the parasite body wall
03

Disease associations

Infection (Lymphatic filariasis, Onchocerciasis, other filarial diseases)

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