FKBP14 antisense RNA 1 (FKBP14-AS1)

FKBP14 antisense RNA 1 (FKBP14-AS1) is a genomic RNA gene classified as a long non-coding RNA (lncRNA), transcribed in the antisense direction with respect to the FKBP14 protein-coding gene[7][3]. FKBP14-AS1 is listed in disease gene panels for Ehlers-Danlos syndrome, kyphoscoliotic type 2, due to its genomic proximity, but its specific biological function and clinical relevance remain unknown[2][7]. No direct biological function, disease role, or therapeutic significance is established, nor are there described molecular interactors or drugs targeting this lncRNA in current literature[7][3]. FKBP14-AS1 is a lncRNA gene, not a classic "target" molecule (such as a receptor or enzyme); it may regulate FKBP14 protein expression by antisense interaction, but this is speculative and unproven in published studies. The "target" FKBP14-AS1 is correctly named for gene annotation purposes, but is not a direct therapeutic target or known clinical biomarker at present[7][3]. If searching for an actionable therapeutic target, FKBP14 (FKBP prolyl isomerase 14/FKBP22) is the protein of relevance[1][5].

Other names

FKBP14-AS1FKBP14 antisense RNA 1NR_187577.1