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FKTN antisense RNA 1 (FKTN-AS1)

Target
FKTN-AS1
Molecular classification
Other (Long non-coding RNA)
01

Overview

FKTN antisense RNA 1 (FKTN-AS1) is a long non-coding RNA transcribed from the antisense strand of the FKTN genomic locus. There is currently no documented biological function, disease association, or therapeutic implication for FKTN-AS1 itself. Drug discovery, therapeutic intervention, and disease mechanism research in the context of Fukuyama congenital muscular dystrophy focus on the FKTN coding gene and its mRNA, particularly via antisense oligonucleotide-mediated exon skipping and splicing modulation; these strategies do not act on FKTN-AS1[1][2][4][6][8]. The FKTN gene encodes ribitol-phosphate transferase, which glycosylates α-dystroglycan, a critical process disrupted in disease, but FKTN-AS1 is not implicated in these pathways in current scientific literature[1][2][4][6].

Other names
FKTN-AS1FKTN antisense RNA 1

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