Target intelligence / Profile preview

Flagellin protein of Pseudomonas aeruginosa (FliC)

Target: FliC
Molecular classification: Structural protein

Overview

The Flagilln protein is the main structural component forming bacterial flagella filaments essential for motility. It undergoes post-translational glycosylation affecting virulence. Recognized by TLR5 activating innate immunity. Key factor in colonization/infection/biofilm formation.

Other names: FliCA-type flagellinB-type flagellinFlagellar filament subunit protein

Biological functions

MotilityPathogenicityBiofilm formationImmune response activation

Disease associations

Infection

Safety considerations

Role in immune activation could complicate therapeutic strategies aimed at modulating its function

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