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Fluid Replacement
- Molecular classification
- Other
01
Overview
"Fluid replacement" describes a therapeutic strategy using various types of fluids—not a molecular target—to restore body water/electrolytes/blood volume via oral/IV/subcutaneous/rectal routes according to clinical need. The choice among available solutions depends on indication-specific factors including urgency/severity/comorbidities/cost/risk profile.
- Other names
- Fluid resuscitation
02
Mechanism of action
Restores body water/electrolytes/blood volume via oral/IV/subcutaneous/rectal routes according to clinical need.
03
Biological functions
Restoration of intravascular volumeCorrection of electrolyte imbalancesMaintenance of tissue perfusion
04
Disease associations
DehydrationHypovolemiaShock
05
Safety considerations
Over-resuscitation leading to edema/pulmonary complicationsRenal injury/coagulopathy with some colloid solutionsPotential worsening of outcomes in traumatic brain injury patients with albumin
06
Interacting drugs
Normal saline
9 more in the full profile.
07
Biomarkers
Normalization of vital signsNormalization of perfusion parametersCentral venous pressure (CVP)
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