Fluorine-19 magnetic resonance imaging (19F MRI)

Fluorine-19 magnetic resonance imaging (19F MRI) is an imaging modality that detects the magnetic resonance (MR) signal from the fluorine-19 (^19F) nucleus, primarily in exogenously administered fluorinated compounds, such as perfluorocarbon-based probes or fluorinated drugs[1][4][6][7]. 19F MRI offers high specificity and quantification capabilities because endogenous fluorine is nearly absent in biological tissues, resulting in negligible background signal[1][4][8]. This technique enables noninvasive tracking and quantification of labeled cells, nanoparticles, or drugs in vivo, and has seen applications in cell tracking, immune monitoring, and drug distribution studies[2][3][4][6]. While 19F MRI is a powerful imaging technique, it is not itself a therapeutic target, enzyme, or receptor, and as such, entries like this are not considered valid molecular targets for drug discovery databases.

Other names

Fluorine-19 MRI19F MR imaging19F magnetic resonance imagingfluorine MRIfluorine MRS