FLVCR1 antisense RNA 1 (FLVCR1-DT)

FLVCR1 antisense RNA 1 (FLVCR1-DT) is a long noncoding RNA gene located adjacent to the protein-coding FLVCR1 gene, which encodes a heme transporter involved in erythropoiesis and neuronal function[2][5][6]. FLVCR1-DT itself is noncoding and presumed to act through regulatory RNA mechanisms, possibly influencing FLVCR1 gene expression, splicing, or chromatin structure. While FLVCR1-DT is sometimes referenced alongside FLVCR1 due to its genomic proximity and antisense orientation, it is not a transporter, receptor, enzyme, or protein, and thus not considered a direct therapeutic target. Most functional studies and disease associations relate to the FLVCR1 protein rather than FLVCR1-DT; however, antisense and divergent transcripts often play roles in molecular regulation or disease through modulation of nearby genes. As of now, no direct biological function, disease mechanism, drug interaction, or biomarker status has been established for FLVCR1-DT itself[5].

Other names

FLVCR1-DTFLVCR1-AS1LQK1NCRNA00292FLVCR1 divergent transcriptFLVCR1 antisense RNA 1 (head to head)FLVCR1 antisense RNA 1 (non-protein coding)