Target intelligence / Profile preview

FLYWCH family member 2 (FLYWCH2)

Target
FLYWCH2
Molecular classification
Other, Zinc finger protein, RNA-binding protein
01

Overview

FLYWCH family member 2 (FLYWCH2) is a protein-coding gene in humans that encodes a protein containing FLYWCH-type zinc finger domains, which are characterized by distinctive sequence motifs with conserved hydrophobic residues[1][3]. FLYWCH2 is annotated with RNA-binding activity, and its related family members are generally involved in functions such as gene transcription, translation, chromatin modulation, or protein-protein interactions, and may participate in diverse cellular processes[1][3]. FLYWCH2 shares significant homology with FLYWCH1 and is not currently described as a therapeutic target or druggable receptor, enzyme, transporter, or channel[3]. Disease relevance has been reported for FLYWCH2 with regard to Allan-Herndon-Dudley Syndrome, but no direct evidence links it to drug targeting or biomarker status[3]. The FLYWCH domain is typically associated with chromatin and protein interactions, but the precise biological function in humans remains to be clarified[1][3].

Other names
FLYWCH2
02

Biological functions

RNA bindingOther
03

Disease associations

Other (association reported with Allan-Herndon-Dudley Syndrome, but not as a therapeutic target)

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