Folinic acid rescue pathway

The entry "Folinic acid rescue pathway" refers to a therapeutic protocol or treatment strategy rather than a molecule, protein, enzyme, receptor, or classical therapeutic target. The "rescue pathway" describes the clinical use of **folinic acid (leucovorin)** to counteract the toxic effects of antifolate drugs such as methotrexate, especially at high doses, by providing a reduced folate that bypasses the blockade of dihydrofolate reductase and permits continued DNA synthesis in normal cells, thus sparing healthy tissues from toxicity[1][2][5][6][7]. **Folinic acid** itself is a molecule and can be considered a drug target in the context of its pharmacological modulation of cytotoxic agents, but "Folinic acid rescue pathway" is not an entity directly targeted by drugs, nor is it a molecular target with specific structure or aliases. The correct subject for structured information as a molecular target would be "Folinic acid" (or "Leucovorin"). If you intended to refer to the molecular target or action of folinic acid itself, information should be requested for "Folinic acid" rather than "Folinic acid rescue pathway"[1][2][5][7].