Follicle stimulating hormone, beta polypeptide pseudogene

Follicle stimulating hormone, beta polypeptide pseudogene (ENSG00000255288) is a nonfunctional genomic DNA sequence related to the FSHB gene, which encodes the beta subunit of follicle stimulating hormone. As a pseudogene, it lacks the ability to produce a functional protein product. Pseudogenes arise from duplication or retrotransposition events but accumulate mutations that prevent expression or functionality. They may be transcribed into RNA, but in most cases, this does not have biological impact, though exceptions are known for regulatory RNAs. This locus is not considered a therapeutic target, nor is it suitable for pharmacological intervention or clinical biomarker use. Key details: This is not a receptor, enzyme, transporter, or other canonical drug target class, but simply a genetic remnant ("pseudogene"). No drugs interact directly with this pseudogene, and there are no safety or biomarker associations. The entry represents a nonfunctional fragment rather than a targetable protein or gene product. Note: The actual hormone target of therapeutic interest is encoded by the functional FSHB gene (follicle stimulating hormone, beta polypeptide), not by its pseudogene. The pseudogene is frequently catalogued for completeness in genomic databases but is irrelevant for drug discovery or clinical applications.

Other names

FSHB pseudogeneENSG00000255288GC11P030188