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Foot temperature monitoring is a clinical strategy and digital health approach primarily used for early detection and prevention of diabetic foot ulcers, particularly in people with diabetes at high risk for foot complications. The principle is that local increases in foot temperature can precede visible signs of inflammation, infection, or tissue breakdown. Technologies include smart insoles, socks with embedded temperature sensors, infrared thermography, and other wearable devices, which enable real-time or continuous assessment at key foot locations. Clinicians use temperature asymmetry (especially differences >2.2°C at similar sites on opposite feet) as a surrogate marker for early inflammation or tissue injury to guide intervention before ulceration occurs. This approach, though not a molecular or drug target, is endorsed in international guidelines for diabetic foot care as a preventive diagnostic method[1][3][2][4].
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