Target intelligence / Profile preview

Forkhead box protein D4-like 3 (FOXD4L3)

Target
FOXD4L3
Molecular classification
Transcription factor
01

Overview

Forkhead box protein D4-like 3 (FOXD4L3) is a protein-coding transcription factor belonging to the forkhead/winged-helix family, implicated in the regulation of gene expression via sequence-specific DNA binding, especially as it relates to RNA polymerase II activity. It is predicted to function in processes such as anatomical structure morphogenesis and cell differentiation. FOXD4L3 has been associated with the genetic disease retinitis pigmentosa 55, but is not commonly considered a direct therapeutic target or linked to any approved drugs[1][2][6][7][8].

Other names
FOXD4L3Forkhead box D4 like 3FOXD6FOXD4BFOXD4L2FOXD4L4OTTHUMG00000019959forkhead box protein D4-like 2forkhead box protein D4-like 4Myeloid factor-gamma
02

Biological functions

Regulation of transcription by RNA polymerase IICell differentiationAnatomical structure morphogenesisSequence-specific DNA binding
03

Disease associations

Retinitis pigmentosa 55

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