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Target intelligence / Profile preview
Forkhead box protein D4-like 5 (FOXD4L5)
- Target
- FOXD4L5
- Molecular classification
- Transcription factor, Forkhead box (FOX) family
01
Overview
Forkhead box protein D4-like 5 (FOXD4L5) is a human protein-coding gene belonging to the forkhead box (FOX) family of transcription factors, which share a conserved DNA-binding domain known as the forkhead or winged-helix domain. FOXD4L5 is predicted to enable sequence-specific DNA binding and regulation of transcription mediated by RNA polymerase II, and may be involved in processes such as cell differentiation and morphogenesis. Its specific functional roles and regulatory targets in human physiology remain uncharacterized, and it is not currently linked to active drug development or considered a validated therapeutic target.
- Other names
- Forkhead box D4-like 5FOXD4-like 5bA15J10.2OTTHUMG00000013332forkhead box protein D4-like 5
02
Mechanism of action
Not applicable (no drugs known to specifically target this protein)
03
Biological functions
Regulation of transcription by RNA polymerase IICell differentiationAnatomical structure morphogenesisDNA-binding transcription factor activity
04
Disease associations
Limited direct evidence. Associated with Arthrogryposis Multiplex Congenita-3 and Fanconi Anemia, Complementation Group B by gene proximity/association but not established as causal
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