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Target intelligence / Profile preview
Forkhead box protein D4-like 6 (FOXD4L6)
- Target
- FOXD4L6
- Molecular classification
- Transcription factor, Forkhead box (FOX) protein family, Helix-turn-helix domain protein
01
Overview
Forkhead box protein D4-like 6 (FOXD4L6) is a human transcription factor belonging to the forkhead box (FOX) protein family, characterized by a conserved winged-helix DNA-binding domain. It is predicted to regulate transcription by RNA polymerase II and is involved in anatomical structure morphogenesis and cell differentiation. FOXD4L6 is not currently considered a classical therapeutic target. Diseases associated with this gene include chondroid chordoma and Usher syndrome type IIa. FOXD4L6 is classified as a DNA-binding transcription factor and does not have established roles as a biomarker or interact directly with drugs[1][2][3][4][5][12].
- Other names
- FOXD4L6FOXD4-like 6Forkhead box protein D4-like 6OTTHUMG00000066822forkhead box protein D4-like 6
02
Biological functions
Regulation of transcription by RNA polymerase IIDNA-binding transcription factor activityAnatomical structure morphogenesisCell differentiation
03
Disease associations
Chondroid chordomaUsher syndrome type IIaOther (no strong evidence for cancer, inflammation, or major disease association in FOXD4L6 specifically; some FOX family members are implicated in cancer progression and other pathologies)
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