Frataxin pseudogene 1 (FXNP1)

Frataxin pseudogene 1 (FXNP1) is a genomic DNA sequence similar to the functional frataxin gene (FXN), but lacks the ability to produce protein due to mutations or deletions that disrupt the coding region. Genuine frataxin (produced by the FXN gene) is crucial for mitochondrial iron-sulfur cluster biosynthesis, and mutations in the FXN gene cause Friedreich's ataxia, a neurodegenerative disease[1][5][3]. However, FXNP1 does not encode a protein, has no known biological function, and is not a receptor, enzyme, transporter, or other druggable target. It should not be used as a target in therapeutic research or biomarker development. Clarification: If your intention was to refer to the functional frataxin gene/protein (FXN) rather than FXNP1, please specify, as FXN is a well-established mitochondrial protein implicated in energy metabolism and Friedreich's ataxia[3][1][5][4]. FXNP1, as a pseudogene, should be excluded from structured drug target databases and resources.

Other names

FXNP1