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Free Aldehydes
- Molecular classification
- Organic compounds, Carbonyl compounds
01
Overview
Free aldehydes are organic compounds containing a functional group with the structure R−CH=O. They are characterized by a carbonyl group bonded to a hydrogen atom and an alkyl or aryl group. While not direct therapeutic targets themselves, their reactivity and presence in metabolic pathways make them relevant in biological contexts. They can be problematic in drug discovery due to their potential for non-specific interactions.
- Other names
- AldehydesR-CHOFormyl group containing compounds
02
Biological functions
Metabolic intermediateFlavoring agentAroma compoundBuilding block for synthesis
03
Disease associations
Related to diseases via metabolic dysregulationContributor to oxidative stress (due to oxidation to carboxylic acids)
04
Safety considerations
Non-specific protein modificationPotential for false positives in drug screening assaysReactivity with biological molecules
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