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Free Radical Scavenger
- Molecular classification
- Enzyme, Small Molecule, Vitamin
01
Overview
A free radical scavenger is a substance, often an antioxidant, that protects cells from damage caused by free radicals. It neutralizes reactive oxygen species (ROS) and other free radicals, preventing oxidative stress and cellular damage. These scavengers can be enzymatic (e.g., catalase, superoxide dismutase) or non-enzymatic (e.g., vitamins C and E). The mechanism of action involves hydrogen atom transfer, single electron transfer, or sequential proton loss electron transfer. Free radical scavengers play a role in various diseases linked to oxidative stress and are explored as therapeutic adjuncts.
- Other names
- AntioxidantReactive Oxygen Species ScavengerROS Scavenger
02
Mechanism of action
Hydrogen Atom Transfer (HAT), Single Electron Transfer followed by Proton Transfer (SET-PT), Sequential Proton Loss Electron Transfer (SPLET)
03
Biological functions
Neutralization of free radicalsReduction of oxidative stressCellular protection
04
Disease associations
CancerInflammationNeurodegenerative diseaseCardiovascular diseaseAgingSepsisAcute Respiratory Distress Syndrome
05
Safety considerations
Potential for pro-oxidant effects at high dosesInterference with redox signaling pathwaysVariability in efficacy depending on the specific antioxidant and context
06
Interacting drugs
Ascorbic Acid (Vitamin C)
3 more in the full profile.
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