FREM2 antisense RNA 1 (FREM2-AS1)

FREM2 antisense RNA 1 (FREM2-AS1) is a long non-coding RNA (lncRNA) gene located on human chromosome 13 (reverse strand, GRCh38: 38,821,798-38,827,570)[5]. It is transcribed as an antisense RNA relative to the FREM2 gene and is catalogued under the NCBI Gene accession number 100874073[3]. To date, its precise biological roles, disease relevance, and potential as a therapeutic or diagnostic target remain unexplored, and it is not listed as a canonical therapeutic target in public databases. FREM2-AS1 may have regulatory functions typical of lncRNAs (e.g., modulation of gene expression in cis or trans), but explicit data for this transcript is lacking in the current genetic and biomedical literature[3][5].