Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Frizzled class receptor 5 (FZD5)
- Target
- FZD5
- Molecular classification
- GPCR, Frizzled family receptor
01
Overview
FZD5 is a cell surface receptor for Wnt signaling proteins, acting as the primary receptor for ligands such as WNT3A, WNT5A, WNT7A, and WNT10B. It activates both canonical (β-catenin-dependent) and non-canonical pathways. FZD5 plays critical roles during embryonic development and adult tissue homeostasis, and its dysregulation has been implicated in several cancers and neurodegenerative diseases.
- Other names
- Frizzled-5Fz-5C2orf31HFZ5frizzled class receptor 5
02
Mechanism of action
Not applicable
03
Biological functions
Wnt signalingNeurogenesisAxon guidanceDendritogenesisEpithelial-mesenchymal transition preventionCellular senescence regulationEye developmentSignal transduction
04
Disease associations
ColobomaInferior chorioretinal hypoplasiaHigh myopiaCancerNeurodegenerative diseasesALS
Beyond the preview
Go deeper on Frizzled class receptor 5 (FZD5).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Frizzled class receptor 5 (FZD5).