FSHD region gene 2 family member F, pseudogene (FRG2FP)

FRG2FP (FSHD region gene 2 family member F, pseudogene) is annotated as a pseudogene related to the FRG2 family and is not protein-coding. The FRG2 gene family members are dispersed across the human genome, and some are located in proximity to the D4Z4 repeat region on chromosomes 4 and 10, which is notable due to its role in facioscapulohumeral muscular dystrophy (FSHD)[1][5]. While the parent gene, FRG2, has been studied for transcriptional upregulation in FSHD patient muscle cells, pseudogene family members like FRG2FP have no known function, encode no protein, and are not considered therapeutic targets. There is no evidence of a molecular function, involvement in disease, or interaction with drugs for FRG2FP. This entity is likely returned in some datasets due to genomic proximity to disease-associated regions, but as a pseudogene, it does not encode a functional product and has no established role as a drug target or biomarker[1][5].

Other names

TCONS_l2_00020053