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Fumarylacetoacetate hydrolase domain containing 1 pseudogene
- Molecular classification
- Other, Pseudogene
01
Overview
The Fumarylacetoacetate hydrolase domain containing 1 pseudogene (ENSG00000259191) is a genomic locus classified as a pseudogene—a DNA sequence that resembles the functional gene (FAHD1), but does not encode a functional protein product[7][4][2]. Pseudogenes usually arise due to gene duplication or retrotransposition and accumulate disabling mutations (such as premature stop codons), preventing expression of an active protein. While some pseudogenes have regulatory roles at the RNA level, there are no reports of any significant biological activity, therapeutic target significance, or biomarker use for this particular pseudogene. It should not be confused with the similarly named, functional FAHD1 gene, which encodes an active mitochondrial oxaloacetate decarboxylase enzyme[1][3].
- Other names
- FAHD1 pseudogeneFumarylacetoacetate hydrolase domain containing 1 (FAHD1) pseudogene
02
Biological functions
OtherDoes not encode a functional protein; no direct biological function
03
Disease associations
OtherNo established direct role in disease; some pseudogenes regulate related genes or may be transcribed, but none are established for this locus
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