Target intelligence / Profile preview

FUN14 domain containing 2 pseudogene 2 (FUNDC2P2)

Target
FUNDC2P2
Molecular classification
Pseudogene, Processed pseudogene, Other
01

Overview

FUN14 domain containing 2 pseudogene 2 (FUNDC2P2) is a human processed pseudogene highly homologous to the functional gene FUNDC2. While its canonical open reading frame is disrupted, sequence analysis and proteomic data suggest potential alternative translation resulting in a truncated form containing the FUN14 domain. Its expression has been observed in human testis and across Old World primates, indicating possible evolutionary conservation. Pseudogenes generally lack protein-coding function but may have regulatory or genomic effects, including modulation of gene networks or impact on disease through mechanisms such as epigenetic silencing, genetic fusion, or mutagenesis. However, FUNDC2P2 has no recognized role as a therapeutic target and no direct disease association established[1][3][5].

Other names
FUNDC2P2FUN14 domain containing 2 pseudogene 2HGNC:17247NCBI Gene: 388965Ensembl: ENSG00000182814GC02P084517GC02P084412
02

Mechanism of action

None. No mechanisms of drug action established for this gene, due to its classification as a pseudogene

03

Biological functions

No established functional activity as a protein. May have non-coding regulatory effects (e.g., transcript regulation, possible involvement in gene expression modulation)
04

Disease associations

Other. Pseudogenes, including FUNDC2P2, can have disease associations indirectly in some contexts (e.g., epigenetic regulation, fusion events, or mutagenesis), but no direct disease role specific to FUNDC2P2 is established

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