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Target intelligence / Profile preview
FUN14 domain containing 2 pseudogene 3 (FUNDC2P3)
- Target
- FUNDC2P3
- Molecular classification
- Pseudogene
01
Overview
"FUN14 domain containing 2 pseudogene 3" (FUNDC2P3) is a human pseudogene that does not encode a protein and is not considered a therapeutic target. The functional gene of this family is FUN14 domain containing 2 (FUNDC2), which is a mitochondrial outer membrane protein implicated in mitochondrial dynamics, cancer progression, and cardiomyopathy. FUNDC2P3 is distinct from FUNDC2; the parent gene's protein is linked to mitochondrial fragmentation through interactions with mitofusin 1, and regulation of ferroptosis via SLC25A11 affecting glutathione transport and heart injury, whereas the pseudogene has no documented biological or therapeutic relevance[2][3][4][5][8][9].
- Other names
- FUNDC2P3FUN14 domain containing 2 pseudogene 3
02
Mechanism of action
Not applicable; no mechanisms defined for pseudogenes.
03
Biological functions
None (as a pseudogene, it does not have documented biological activity)
04
Disease associations
None documented for the pseudogene itself, though the parent gene FUNDC2 has been implicated in cancers and cardiomyopathy
05
Safety considerations
None; pseudogenes are not therapeutic targets.
06
Interacting drugs
None known; drugs interact with the functional protein FUNDC2, not the pseudogene
07
Biomarkers
None for pseudogene; parent gene FUNDC2 is being studied in liver cancer as a potential biomarker
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