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Functional brain network connectivity

Molecular classification
Other (not a molecule, receptor, enzyme, or protein; refers to a systems-level property)
01

Overview

Functional brain network connectivity refers to the statistical dependencies or correlations between spatially separated regions of the brain that reflect coordinated neural activity. It is not a single molecule, receptor, or drug target but rather a systems-level property measured using neuroimaging techniques such as fMRI and EEG. Functional connectivity is often assessed during resting-state conditions but can also be studied during tasks. It provides insight into how different parts of the brain communicate and integrate information to support cognitive functions. Alterations in these patterns have been associated with various neurological and psychiatric diseases, making them an area of interest for biomarker development and understanding disease mechanisms[1][2][3][4]. **Note:** "Functional brain network connectivity" is not a molecular target such as a receptor or enzyme; it describes an emergent property at the level of neural networks. Therefore, it does not fit standard classifications used for therapeutic targets in pharmacology or molecular biology.

Other names
Functional connectivityBrain functional network connectivityResting-state functional connectivity (in specific contexts)
02

Biological functions

Information processing in the brainCognitive function integrationCoordination of neural activity across regions
03

Disease associations

Neurodegenerative disease (e.g., Alzheimer's disease)Psychiatric disorders (e.g., schizophrenia)DementiaMultiple sclerosisOther neurological and mental disorders
04

Biomarkers

Patterns of altered functional connectivity are being explored as biomarkers for neurological and psychiatric diseases

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