Target intelligence / Profile preview

Functional electrical stimulation (FES)

Target
FES
Molecular classification
Other
01

Overview

Functional electrical stimulation (FES) is not a molecule, protein, enzyme, or receptor but rather a therapeutic technique that uses low-energy electrical impulses to induce muscle contractions in individuals with paralysis or muscle weakness due to central nervous system injuries such as stroke, spinal cord injury, or multiple sclerosis. FES works by applying electrical currents to peripheral nerves, thus generating muscle movement to restore or improve functions such as walking, grasping, standing, or bladder control. It is used for both long-term assistance (neuroprosthesis) and short-term rehabilitation to retrain or recover voluntary motor function. While FES can improve muscle mass, strength, and cardiovascular health, as well as reduce muscle atrophy and secondary health complications, it is associated with certain risks and is not appropriate for all patients[1][2][3][4][5][6][9][10]. Important Note: "Functional electrical stimulation" is not a molecular target, but a medical device-based therapeutic technique. Therefore, it is not appropriate to list this under molecular or receptor targets; thus, "is_target" is false and "is_incorrect" is true for your specified schema.

Other names
Functional electrical stimulation (FES)Functional electrical stimulation therapyFES therapy (FET or FEST)Neuromuscular electrical stimulation (NMES)
02

Biological functions

Muscle contraction (therapeutic induction)Rehabilitation of movementNeuromuscular modulationRestoration of motor functionPromotion of neuroplasticity
03

Disease associations

Stroke rehabilitationMultiple sclerosis motor impairmentSpinal cord injuryNeurological disorders (general)ParaplegiaMuscle atrophy prevention
04

Safety considerations

Possible fracture risk due to osteoporosis or low bone densityRisk of autonomic dysreflexia in high-level spinal cord injuryNot suitable for severe spasticity or contracturesDiscomfort due to electrical stimulation

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