Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Fungal Cytoplasmic Membrane (Plasma Membrane)
- Target
- Plasma Membrane
- Molecular classification
- Lipid Bilayer, Membrane
01
Overview
The fungal cytoplasmic membrane, also known as the plasma membrane, is a critical structure in fungal cells. It serves as a selective barrier between the cell's interior and its external environment, regulating the transport of molecules and ions in and out of the cell. It is characterized by specific components such as ergosterol, which distinguishes it from animal or plant cell membranes. It is a major target for antifungal drugs.
- Other names
- Fungal Plasma MembraneCell Membrane (Fungal)Plasma Membrane
02
Mechanism of action
Polyenes bind to ergosterol, causing pore formation; Azoles inhibit ergosterol biosynthesis.
03
Biological functions
Selective permeability barrierIon transportNutrient transportProtein traffickingLipid traffickingSignal transductionElectrochemical gradient maintenancepH regulationCell wall synthesis anchoring
04
Disease associations
Infection (Fungal)Antifungal resistance
05
Safety considerations
Drug resistanceToxicity of antifungal drugsDrug-drug interactions
06
Interacting drugs
Polyene antifungals (e.g., Amphotericin B, Nystatin)
1 more in the full profile.
Beyond the preview
Go deeper on Fungal Cytoplasmic Membrane (Plasma Membrane).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Fungal Cytoplasmic Membrane (Plasma Membrane).