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The "fungal RNA synthesis machinery" encompasses both general transcription mechanisms shared across eukaryotes as well as specialized regulatory pathways such as those mediated by the conserved core proteins Dicer, Argonaute, and RdRP within the fungal kingdom. These machineries are central not only to basic gene expression but also genome defense mechanisms unique to many fungi through diverse implementations of small-RNA-mediated silencing pathways.
Inhibition of RNA synthesis or RNAi pathway components
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