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Target intelligence / Profile preview
Respiratory Syncytial Virus Fusion Glycoprotein F (RSV-F)
- Target
- RSV-F
- Molecular classification
- Viral Fusion Protein, Glycoprotein, Type I transmembrane protein
01
Overview
The respiratory syncytial virus fusion glycoprotein (F) is indispensable for initiating infection through membrane fusion. Its structural dynamics between prefusion and postfusion states underpin both its biological function and significance as a vaccine antigen. Targeting this molecule remains central to current strategies against RSV disease across all age groups.
- Other names
- F proteinRSV F proteinFusion glycoprotein
02
Mechanism of action
Neutralizing antibody; binds to RSV F protein, preventing fusion and entry.
03
Biological functions
Membrane fusionViral entryCell-to-cell spreadReceptor binding
04
Disease associations
Respiratory Syncytial Virus Infection
05
Interacting drugs
Palivizumab
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