FZD4 divergent transcript (FZD4-DT)

FZD4 divergent transcript (FZD4-DT) is an lncRNA gene located near the FZD4 gene, which encodes Frizzled 4, a G protein-coupled receptor involved in Wnt signaling. Unlike the protein-coding FZD4, FZD4-DT has not been demonstrated to encode a receptor, enzyme, or other conventional therapeutic target. Its biological functions, disease relevance, and molecular mechanisms remain uncharacterized in the published literature. FZD4-DT should not be confused with the Frizzled 4 receptor (FZD4), which is a well-studied therapeutic target in ophthalmological and vascular disorders[3]. If you are searching for information on the Frizzled 4 receptor, use "Frizzled 4" or "FZD4" instead of "FZD4-DT". FZD4-DT designates a noncoding RNA and is not a drug target in its own right[3].

Other names

FZD4-DTFZD4 divergent transcript