G protein-coupled receptor 128 pseudogene

The "G protein-coupled receptor 128 pseudogene" (ENSG00000271779) is a genomic region that is similar in sequence to the protein-coding GPR128/ADGRG7 gene, but it is classified as a pseudogene, meaning it does not encode a functional receptor protein. Pseudogenes are remnants of ancestral genes that have lost their protein-coding ability through mutations or deletions and are not considered drug targets. The functional GPR128 (now ADGRG7) encodes a member of the adhesion G protein-coupled receptor family involved in some biological processes, but the pseudogene has no function, role in disease, or relevance for drug development[4][3]. In summary, ENSG00000271779 is a non-functional pseudogene and not a viable therapeutic target. If you intended to query the active gene/protein, use “Adhesion G protein-coupled receptor G7” (ADGRG7, formerly GPR128)—not this pseudogene—for target information[4][3].