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Target intelligence / Profile preview
G protein-coupled receptor 143 Y-linked pseudogene (GPR143YP)
- Target
- GPR143YP
- Molecular classification
- Other (pseudogene)
01
Overview
G protein-coupled receptor 143 Y-linked pseudogene (GPR143YP) is a segment of DNA on the Y chromosome that is homologous to the protein-coding gene *GPR143*, which is crucial for pigmentation and implicated in ocular albinism type 1. GPR143YP does **not encode a functional protein** and therefore is not a molecular target for therapeutic intervention[3]. The functional *GPR143* gene (on the X chromosome) encodes an atypical G protein-coupled receptor involved in intracellular signaling in pigment cells, but the Y-linked pseudogene plays no functional role in physiology, disease, or drug action.
- Other names
- GPR143YGPR143POA1PG protein-coupled receptor 143 pseudogeneocular albinism 1 (Nettleship-Falls) Y-linked pseudogeneGPR143YP
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